Contemporary Guide to Aesthetic Enhancement

Contemporary guide to aesthetic enhancementMarian Cantisano-Zilkha (Author), MD (Author), PhD (Author)
Aesthetic enhancement procedures are no longer the exclusive purview of the cosmetic surgeon. This new handbook by a leading authority on aesthetic enhancement explains the various minimally invasive procedures that primary care physicians can perform in office to improve the appearance of their patients. Includes a full-color insert of before-and-after photos. With a foreword by William Hanke, MD, MPH.

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Dermoscopy Image Analysis

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Dermoscopy Image Analysis

M. Emre Celebi; Teresa Mendonca; Jorge S. Marques
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Dermoscopy is a noninvasive skin imaging technique that uses optical magnification and either liquid immersion or cross-polarized lighting to make subsurface structures more easily visible when compared to conventional clinical images. It allows for the identification of dozens of morphological features that are particularly important in identifying malignant melanoma.

Dermoscopy Image Analysis summarizes the state of the art of the computerized analysis of dermoscopy images. The book begins by discussing the influence of color normalization on classification accuracy and then: Investigates gray-world, max-RGB, and shades-of-gray color constancy algorithms, showing significant gains in sensitivity and specificity on a heterogeneous set of images Proposes a new color space that highlights the distribution of underlying melanin and hemoglobin color pigments, leading to more accurate classification and border detection results Determines that the latest border detection algorithms can achieve a level of agreement that is only slightly lower than the level of agreement among experienced dermatologists Provides a comprehensive review of various methods for border detection, pigment network extraction, global pattern extraction, streak detection, and perceptually significant color detection Details a computer-aided diagnosis (CAD) system for melanomas that features an inexpensive acquisition tool, clinically meaningful features, and interpretable classification feedback Presents a highly scalable CAD system implemented in the MapReduce framework, a novel CAD system for melanomas, and an overview of dermatological image databases Describes projects that made use of a publicly available database of dermoscopy images, which contains 200 high-quality images along with their medical annotations

Dermoscopy Image Analysis not only showcases recent advances but also explores future directions for this exciting subfield of medical image analysis, covering dermoscopy image analysis from preprocessing to classification.

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Advances in Pharmaceutical Cell Therapy : Principles of Cell-Based Biopharmaceuticals

Ralf Huss; Christine Guenther; Andrea Hauser
>This textbook is a comprehensive overview of the development of cell-based biopharmaceuticals. Beginning with the underlying biology of stem cell and cell-based products, it traces the long and complex journey from preclinical concept to initiation of a pivotal clinical trial and the potential business model behind it.The book also takes into consideration the different regulatory landscapes and their continuous evolution in Europe, North America and other parts of the world. The authors describe a path to manufacture a clinical grade therapeutic that passes all necessary quality measures as a robust and marketable product including an outlook on next generation products and innovative strategies.This reference book is a must-have guide for any professional already active in biopharmaceuticals and anyone interested in getting involved in a scientific, medical or business capacity.

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Forensic Chemistry : Fundamentals and Applications

Jay A. Siegel
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Forensic Chemistry is a comprehensive overview of the subject aimed at those students who have a basic understanding of the underlying principles and are looking for a more detailed reference text. This book is aimed at advanced students who are studying forensic science or analytical chemistry, faculty and researchers, and practitioners such as crime laboratory bench scientists. The authors will assume that the reader will have an introductory knowledge of forensic science and forensic chemistry and will have had analytical, organic and instrumental chemistry. None of the major analytical chemical techniques will have separate treatments in the book, with the exception of forensic microscopy, which will have a chapter because many students in chemistry and forensic science do not get dedicated classes in this area. The book will have separate chapters on all of the major areas of forensic chemistry and, in addition, will have a chapter devoted to chemometrics, which is the statistical treatment of large amounts of data to discover groupings, similarities and differences among the data. Each chapter will be written by an acknowledged international expert in that area. Each author will be given detailed instructions as to the intended audience, as well as expected breadth and depth of coverage of the material in the hopes that this will minimize the problem of uneven coverage of topics and chapters that often occurs in edited books. Although each of the types of evidence covered in the book use methods of analysis that lie outside chemistry, these will be mentioned only for completeness in passing. The emphasis will be on the use of chemical tools in evidence analysis.

This book is designed to be either a text book for an advanced forensic chemistry course, or a treatise in forensic chemistry for the scientist who wants to learn the subject in some depth. It is not designed to be a survey of the current literature in the field or a reference manual.

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